https://www.youtube.com/watch?v=R-VJkyl8PeY
/mnt/1T-5e7/mycodehtml/Biology/SangSooKim/Bioinformatics_basic/005/003_Gene_database/main.html
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Gene XIAP has 2 mRNAs as alternative splicing
- How can you know "gene XIAP has 2 mRNAs"?
- In Nucleotide database, search XIAP
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Gene XIAP is in various living creatures
Human being
Mouse
Chimpanzee
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Click
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Click
RefSeq:
- Many researchers upload their result sequence onto the corresponding database
- NCBI removes duplicated results
- And NCBI creates RefSeq which contains no duplicated data
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- mRNA_1 for XIAP gene
- mRNA_2 for XIAP gene
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- non-coding RNA
click
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- Gene: XIAP
- Alternative splicing: transcription variant 3
- Axon/intron: intron (non-coding RNA)
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- NG: DNA sequence (axon+intron)
- much more longer
Click
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There is one more XM as alternative splicing
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- NM: mature mRNA
- XM: predicted model-mRNA which is not proved in experiments
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- Transcription on XM, and get predicted model-protein-products
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- If you search "XIAP" and "Human" and "mRNA", click
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- Be careful on "associated factors"
- These are not XIAP, but XAF1 gene which is related to XIAP
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Another way to get same result
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This is translated
into
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- Researchers confirmed the result
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Click
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